75 year Anniversary Spreading Depolarizations
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The Co-Operative Studies on Brain Injury Depolarizations is an international research consortium focused on the role of spreading depolarizations in acute neurologic injury.

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The Problem: Brain Tsunamis

Spreading depolarizations are waves of electrical silence caused by mass neuronal depolarizations in injured brain. These occur in traumatic brain injury, ischemic stroke, aneurysmal SAH and ICH.

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Spreading Ischemia

Spreading depolarizations also elicit profound changes in cerebral blood flow. These changes can help brain tissue recover, or in pathologic conditions, may worsen injury through a process known as spreading ischemia.

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Translation: Bench and Bedside

COSBID develops insights into acute brain injury through clinical and basic science research. This documentary film tells the story of translation from Leao (1944) to present day, and provides an introduction of methods and concepts for those new to the field.




Annual meeting registration open!

We are looking forward to seeing you at the International Conference on Spreading Depolarizations (iCSD) held from November 13th to 17th, 2024, in Antalya, Türkiye.

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See our previous meeting!

Look back at last year’s iCSD held in October 2nd to 5th in Szeged, Hungary.

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Obituary: Justin S. Cetas

It is with heavy hearts and a deep sense of loss that we share with you the tragic news of the sudden passing of our dear colleague Justin S. Cetas on July 13th, 2022.

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Visit braintsunamis.com for a self-study guide and tutorials on spreading depolarizations.

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